Vrije Universiteit Brussel


Research Page of Bieke Dejaegher

Last update: 10/09/2013

General Information

CIVIL STATUS :

  • Born December 25th 1978 in Kortrijk (Belgium).

  • Belgian nationality

  • Married to Kenny Molly

EDUCATION :

  • July 3th 2003 : Degree in Pharmaceutical Sciences obtained at the Vrije Universiteit Brussel (VUB) - Belgium - Faculteit Geneeskunde en Farmacie

  • Training in experimental design :
    Méthodologie de la Recherché Expérimentale: Nouveaux outils de planification expérimentale - LPRAI - May 15th-18th 2006 - Aix-en-Provence - France

  • May 29th 2007 : Degree of Ph.D. in Pharmaceutical Sciences obtained
    Title : "New aspects in robustness testing"
    Promotors : Prof. Dr. Y. Vander Heyden and Prof. Dr. J. Smeyers-Verbeke

ACADEMIC CAREER :

  • September 1st 2003 - September 30th 2007 : Ph.D. student in Pharmaceutical Sciences, Department of Analytical Chemistry and Pharmaceutical Technology (FABI)
    Vrije Universiteit Brussel (VUB) - Belgium

  • October 1st 2003 - September 30th 2007 : Ph.D. studies are funded by a specialisation grant awarded by the OZR (Onderzoeksraad) in Flanders

  • Since October 1st 2007 : Postdoctoral Fellow of the Research Foundation - Flanders (FWO)

  • Since October 1st 2009 : Guestprofessor ("docent")
    Erasmus Hogeschool Brussel (EhB) - Campus Jette - Belgium
    Bachelor in Biomedical Laboratory Technology ("Bachelor in Biomedische Laboratoriumtechnologie")
    Title course 2009-2010 : Instrumental Analysis ("Instrumentele Analyse")
    Title course 2010-2011 and 2011-2012 : Analytical Chemistry 2 ("Analytische Chemie 2")

  • Since October 1st 2010 : 10% ZAP at the Vrije Universiteit Brussel, Department of Analytical Chemistry and Pharmaceutical Technology (FABI)

PRIZES / AWARDS :

STAYS ABROAD :

  • September 13th-17th 2010 :
    "Introductory Course to Chemometrics: Experimental Design and Multivariate Data Analysis",
    Yvan Vander Heyden and Bieke Dejaegher,
    Bee Research Institute, Chinese Academy of Agricultural Sciences, Beijing, P.R. CHINA

  • April 1st - June 30th 2012 :
    "Semi-supervised classification of analytical data",
    Université Lille-Nord de France, Department LASIR, Lille, France (Dr. Cyril Ruckebusch)
    Funded with a Research Foundation - Flanders (FWO) grant

RESEARCH TOPICS :

  • Chemometrics :
    • Experimental designs for method development and method validation/robustness testing
      • Factorial designs, Plackett-Burman designs, Central composite designs,
      • Less frequently applied designs: Supersaturated designs, Uniform designs, Rechtschaffner designs.
    • Method capability, Six Sigma
    • Randomization tests
    • Multiple regression methods (backward, forward, stepwise, ridge regression)
    • Multicomponent analysis with MLR and PLS
    • (Pre-)treatment of HPLC fingerprints
    • Quantitative Structure-Activity Relationship (QSAR) and Quantitative Structure-Retention Relationship (QSRR) modeling
    • Process Analytical Technology (PAT)

  • Analytical chemistry :
    • FIA
    • Fast separations on classical HPLC columns
    • Fingerprint chromatography (HPLC)


Publications

    In books

  • [1] "Robustness tests of CE methods",
    B. Dejaegher and Y. Vander Heyden,
    In: M. Jimidar and S. Ahuja (Eds), Capillary Electrophoresis Methods for Pharmaceutical Analysis, Chapter 9, Elsevier, Amsterdam, 2008, pp. 185-224
    doi:10.1016/S0149-6395(07)00009-8

  • [2] "Sequential optimization methods",
    B. Dejaegher and Y. Vander Heyden,
    In: S. Brown, R. Tauler and B. Walczak (Eds), Comprehensive Chemometrics, Volume 1, Chapter 17, Elsevier, Oxford, 2009, pp. 547-575
    doi:10.1016/B978-044452701-1.00036-3

  • [3] "Experimental design in method optimization and robustness testing",
    B. Dejaegher, A. Durand, and Y. Vander Heyden,
    In G. Hanrahan and F.A. Gomez (Eds), Chemometric Methods in Capillary Electrophoresis, Chapter 2, John Wiley & Sons, New Jersey, 2010, pp. 11-74
    doi:10.1002/9780470530191.ch2

  • [4] "Exploratory data analysis and classification of capillary electrophoretic data",
    M. Dumarey, B. Dejaegher, A. Durand, and Y. Vander Heyden,
    In G. Hanrahan and F.A. Gomez (Eds), Chemometric Methods in Capillary Electrophoresis, Chapter 13, John Wiley & Sons, New Jersey, 2010, pp. 291-322
    doi:10.1002/9780470530191.ch13

  • [5] "Chromatographic development, validation, and data handling of tea fingerprints",
    B. Dejaegher and Y. Vander Heyden,
    In V.R. Preedy (Ed), Tea in Health and Disease Prevention, Chapter 27, Academic Press, Elsevier, Amsterdam, pp. 323-333
    doi: 10.1016/B978-0-12-384937-3.00027-6

  • [6] "Validation of gas chromatographic methods",
    B. Dejaegher, J. Smeyers-Verbeke, and Y. Vander Heyden,
    In C.F. Poole (Ed), Handbooks of Separation Science: Gas Chromatography, Chapter 18, Elsevier, Amsterdam, pp. 437-451
    doi: 10.1016/B978-0-12-385540-4.00018-3

  • [7] "Experimental design methodologies in the optimization of chiral CE or CEC separations",
    B. Dejaegher, D. Mangelings, and Y. Vander Heyden,
    In G. Scriba (Ed), Chiral Separations - Methods and Protocols, In John M. Walker (Series Ed), Methods in Molecular Biology, Chapter 26, Humana Press, pp. 409-428
    doi: 10.1007/978-1-62703-263-6_26

  • [8] "Multivariate data analysis",
    B. Dejaegher,
    In K. Hostettmann, A. Marston, H. Stuppner, and S. Chen (Eds), Handbook of Chemical and Biological Plant Analytical Methods, Chapter 72, Wiley, In revision

    In journals

  • [1] "The variance of screening and supersaturated design results as a measure for method robustness",
    B. Dejaegher, J. Smeyers-Verbeke, Y. Vander Heyden,
    Analytica Chimica Acta 544 (2005) 268-279 (Special Issue CAC-2004)
    doi:10.1016/j.aca.2004.12.056

  • [2] "Evaluation of chemometric techniques to select orthogonal chromatographic systems",
    E. Van Gyseghem, B. Dejaegher, R. Put, P. Forlay-Frick, A. Elkihel, M. Daszykowski, K. Héberger, D.L. Massart, Y. Vander Heyden,
    Journal of Pharmaceutical and Biomedical Analysis 41 (2006) 141-151
    doi:10.1016/j.jpba.2005.11.007

  • [3] "Randomization tests to identify significant effects in experimental designs for robustness testing",
    B. Dejaegher, X. Capron, J. Smeyers-Verbeke, Y. Vander Heyden,
    Analytica Chimica Acta 564 (2006) 184-200
    doi:10.1016/j.aca.2006.01.101

  • [4] "Robustness tests",
    B. Dejaegher and Y. Vander Heyden,
    LC-GC Europe 19 (7) (2006) 418-423

  • [5] "Improving method capability of a drug-substance HPLC assay",
    B. Dejaegher, M. Jimidar, M. De Smet, P. Cockaerts, J. Smeyers-Verbeke, Y. Vander Heyden,
    Journal of Pharmaceutical and Biomedical Analysis 42 (2006) 155-170
    doi:10.1016/j.jpba.2006.01.001

  • [6] "Data-handling software for a GLP environment: development and validation requirements",
    N. Matthijs, B. Dejaegher, Y. Vander Heyden,
    LC-GC Europe 19 (12) (2006) 656-663

  • [7] "Fixing Effects and Adding Rows (FEAR) method to estimate factor effects in supersaturated designs constructed from Plackett-Burman designs",
    B. Dejaegher, X. Capron, Y. Vander Heyden,
    Chemometrics and Intelligent Laboratory Systems 85 (2007) 220-231
    doi:10.1016/j.chemolab.2006.06.017

  • [8] "Comparison of Plackett-Burman and supersaturated designs in robustness testing",
    B. Dejaegher, M. Dumarey, X. Capron, M.S. Bloomfield, Y. Vander Heyden,
    Analytica Chimica Acta 595 (2007) 59-71 (Special Issue CAC-2006)
    doi:10.1016/j.aca.2006.11.077

  • [9] "Ruggedness and robustness testing" (Review article),
    B. Dejaegher, Y. Vander Heyden,
    Journal of Chromatography A 1158 (2007) 138-157 (Special Issue on Data Analysis)
    doi:10.1016/j.chroma.2007.02.086
    Awarded as one of the Top 50 Most Cited Review Articles published in Journal of Chromatography A 2007-2009.

  • [10] "Generalized FEAR method to estimate factor effects in two-level supersaturated designs",
    B. Dejaegher, X. Capron, Y. Vander Heyden,
    Journal of Chemometrics 21 (2007) 303-323 (Special Issue in honour of Prof. D.L. Massart)
    doi:10.1002/cem.1065

  • [11] "Screening designs - PART I - Types and properties",
    B. Dejaegher, Y. Vander Heyden,
    LC-GC Europe 20 (10) (2007) 526-532

  • [12] "Screening designs - PART II - Data analysis",
    B. Dejaegher, Y. Vander Heyden,
    LC-GC Europe 21 (2) (2008) 96-102

  • [13] "Supersaturated designs: set-ups, data interpretations and analytical applications" (Review article),
    B. Dejaegher, Y. Vander Heyden,
    Analytical and Bioanalytical Chemistry 390 (2008) 1227-1240 (Special Issue on Chemometrics)
    doi:10.1007/s00216-007-1641-0

  • [14] "Validation of a fluorimetric assay for 4-aminophenol in paracetamol tablets",
    B. Dejaegher, M.S. Bloomfield, J. Smeyers-Verbeke, Y. Vander Heyden,
    Talanta 75 (2008) 258-265
    doi:10.1016/j.talanta.2007.11.029

  • [15] "Method development for HILIC assays" (Review article),
    B. Dejaegher, D. Mangelings, Y. Vander Heyden,
    Journal of Separation Science 31 (2008) 1438-1448 (Special Issue on HILIC)
    doi:10.1002/jssc.200700680

  • [16] "Direct Orthogonal Signal Correction as preprocessing technique for near infrared applications",
    A. Durand, B. Dejaegher, J. Luypaert, Y. Vander Heyden,
    NIR news 19 Issue 2 (2008) 4-5

  • [17] "Raman spectroscopy as a process analytical technology (PAT) tool for the in-line monitoring and understanding of a powder blending process",
    T.R.M. De Beer, C. Bodson, B. Dejaegher, B. Walczak, P. Vercruysse, A. Burggraeve, A. Lemos, L. Delattre, Y. Vander Heyden, J.P. Remon, C. Vervaet, W.R.G. Baeyens,
    Journal of Pharmaceutical and Biomedical Analysis 48 (2008) 772-779
    doi:10.1016/j.jpba.2008.07.023

  • [18] "Polyphenols isolated from antiradical extracts of Mallotus metcalfianus",
    C. Rivière, V. Nguyen Thi Hong, L. Pieters, B. Dejaegher, Y. Vander Heyden, M. Chau Van, J. Quetin-Leclercq,
    Phytochemistry 70 (2009) 91-99
    doi:10.1016/j.phytochem.2008.10.008

  • [19] "Critical analysis of the SCCNFP/SCCP safety assessment of cosmetic ingredients (2000-2006)",
    M. Pauwels, B. Dejaegher, Y. Vander Heyden, V. Rogiers,
    Food and Chemical Toxicology 47 (2009) 898-905
    doi:10.1016/j.fct.2009.01.026

  • [20] "The use of experimental design in separation science" (Tutorial article),
    B. Dejaegher, Y. Vander Heyden,
    Acta Chromatographica 21 (2) (2009) 161-201
    doi:10.1556/AChrom.21.2009.2.1

  • [21] "Evaluation of a generalized use of the log Sum(k+1)AA descriptor in a QSRR model to predict peptide retention on RPLC systems",
    K. Bodzioch, B. Dejaegher, T. Baczek, R. Kaliszan, Y. Vander Heyden,
    Journal of Separation science 32 (2009) 2075-2083
    doi:10.1002/jssc.200900030

  • [22] "Response surface designs - Part I - Types and properties",
    B. Dejaegher, Y. Vander Heyden,
    LC-GC Europe 22 (5) (2009) 256-261

  • [23] "Evaluation of Artemisia annua infusion efficacy for the treatment of malaria in Plasmodium chabaudi chabaudi infected mice",
    M.A. Atemnkeng, B. Chimanuka, B. Dejaegher, Y. Vander Heyden, J. Plaizier-Vercammen,
    Experimental Parasitology 122 (2009) 344-348
    doi:10.1016/j.exppara.2009.04.004

  • [24] "Identification of significant effects from an experimental screening design in the absence of effect sparsity",
    B. Dejaegher, A. Durand, Y. Vander Heyden,
    Journal of Chromatography B 877 (2009) 2252-2261 (Special Issue on Method Validation, Transfer and Comparison for complex matrices)
    doi:10.1016/j.jchromb.2008.10.019

  • [25] "Improving the capillary electrophoretic analysis of poliovirus using a Plackett-Burman design",
    I. Oita, H. Halewyck, S. Pieters, B. Dejaegher, B. Thys, B. Rombaut, Y. Vander Heyden,
    Journal of Pharmaceutical and Biomedical Analysis 50 (2009) 655-663
    doi: 10.1016/j.jpba.2008.09.049

  • [26] "Development of HPLC fingerprints for Mallotus species extracts and evaluation of the peaks responsible for their antioxidant activity",
    N. Nguyen Hoai, B. Dejaegher, C. Tistaert, V. Nguyen Thi Hong, C. Rivière, G. Chataigné, M. Chau Van, J. Quetin-Leclercq, Y. Vander Heyden,
    Journal of Pharmaceutical and Biomedical Analysis 50 (2009) 753-763
    doi: 10.1016/j.jpba.2009.06.016

  • [27] "Potential antioxidant compounds in Mallotus species fingerprints. Part I: Indication, using linear multivariate calibration techniques",
    C. Tistaert, B. Dejaegher, N. Nguyen Hoai, G. Chataigné, C. Rivière, V. Nguyen Thi Hong, M. Chau Van, J. Quetin-Leclercq, Y. Vander Heyden,
    Analytica Chimica Acta 652 (2009) 189-197 (Special Issue in honour of Prof. A. Townshend)
    doi:10.1016/j.aca.2009.07.020

  • [28]"Development and validation of a normal-phase high-performance thin layer chromatographic method for the analysis of sulfamethoxazole and trimethoprim in co-trimoxazole tablets",
    D.H. Shewiyo, E. Kaale, P.G. Risha, B. Dejaegher, J. Smeyers-Verbeke, Y. Vander Heyden,
    Journal of Chromatography A 1216 (2009) 7102-7107
    doi:10.1016/j.chroma.2009.08.076

  • [29] "Response surface designs - Part II - Data Analysis and Multiresponse Optimization",
    B. Dejaegher, Y. Vander Heyden,
    LC-GC Europe 22 (11) (2009) 581-585

  • [30] "Evaluation of the influence of proline, hydroxyproline or pyrrolidine in the presence of sodium nitrite on N-nitrosamine formation when heating cured meat",
    G. Drabik-Markiewicz, B. Dejaegher, E. De Mey, S. Impens, T. Kowalska, H. Paelinck, Y. Vander Heyden,
    Analytica Chimica Acta 657 (2010) 123-130
    doi:10.1016/j.aca.2009.10.028

  • [31] "Methodology to develop liquid chromatographic fingerprints for the quality control of herbal medicines",
    B. Dejaegher, G. Alaerts, N. Matthijs,
    Acta Chromatographica 22 (2010) 237-258
    doi: 10.1556/AChrom.22.2010.2.7

  • [32] "HILIC methods in pharmaceutical analysis",
    B. Dejaegher, Y. Vander Heyden,
    Journal of Separation Science 33 (2010) 698-715
    doi: 10.1002/jssc.200900742

  • [33] "Method development for drug impurity profiling - Part I",
    B. Dejaegher, M. Dumarey, Y. Vander Heyden,
    LC-GC Europe 23 (4) (2010) 218-224

  • [34] "Emerging analytical separation techniques with high-throughput potential for pharmaceutical analysis - Part I - Stationary phase and instrumental developments in LC",
    S. Pieters, B. Dejaegher, Y. Vander Heyden,
    Combinatorial Chemistry & High Throughput Screening 13 (2010) 510-529

  • [35] "Emerging analytical separation techniques with high-throughput potential for pharmaceutical analysis - Part II - Novel chromatographic modes",
    B. Dejaegher, S. Pieters, Y. Vander Heyden,
    Combinatorial Chemistry & High Throughput Screening 13 (2010) 530-547

  • [36] "Mallotus species from Vietnamese mountainous areas: phytochemistry and pharmacological activities",
    C. Rivière, V. Nguyen Thi Hong, Q. Tran Hong, G. Chataigné, N. Nguyen Hoai, B. Dejaegher, C. Tistaert , T. Nguyen Thi Kim, Y. Vander Heyden, M. Chau Van, J. Quetin-Leclercq,
    Phytochemistry Reviews 9 (2010) 217-253
    doi:10.1007/s11101-009-9152-6

  • [37] "Identification of poliovirions and subviral particles by capillary electrophoresis",
    H. Halewyck, I. Oita, B. Thys, B. Dejaegher, Y. Vander Heyden, B. Rombaut,
    Electrophoresis 31 (2010) 3281-3287
    doi:10.1002/elps.201000274

  • [38] "Development and validation of a normal-phase HPTLC method for the simultaneous analysis of lamivudine, stavudine and nevirapine in fixed-dose combination tablets",
    D.H. Shewiyo, E. Kaale, C. Ugullum, M.N. Sigonda, P.G. Risha, B. Dejaegher, J. Smeyers-Verbeke, Y. Vander Heyden,
    Journal of Pharmaceutical and Biomedical Analysis 54 (2011) 445-450
    doi:10.1016/j.jpba.2010.09.009

  • [39] "Exploratory analysis of chromatographic fingerprints to distinguish Rhizoma Chuanxiong and Rhizoma Ligustici",
    G. Alaerts, M. Merino-Arévalo, M. Dumarey, B. Dejaegher, N. Noppe, N. Matthijs, J. Smeyers-Verbeke, Y. Vander Heyden,
    Journal of Chromatography A 1217 (2010) 7706-7716
    doi:10.1016/j.chroma.2010.10.010

  • [40] "Method development for drug impurity profiling - Part II",
    B. Dejaegher, M. Dumarey, Y. Vander Heyden,
    LC-GC Europe 23 (10) (2010) 536-542

  • [41] "Recent developments in chromatographic fingerprints from herbal products: set-up and data analysis"
    G. Alaerts, B. Dejaegher, J. Smeyers-Verbeke, Y. Vander Heyden,
    Combinatorial Chemistry & High Throughput Screening 13 (2010) 900-922

  • [42] "Pressurized capillary electrochromatography in a screening for possible antioxidant molecules in Mallotus fingerprints: Challenges, potentials and prospects",
    S. Pieters, C. Tistaert , G. Alaerts, K. Bodzioch, D. Mangelings, B. Dejaegher, C. Rivière, N. Nguyen Hoai, M. Chau Van, J. Quetin-Leclerq, Y. Vander Heyden,
    Talanta 83 (2011) 1188-1197
    doi:10.1016/j.talanta.2010.08.006

  • [43] "Dissimilar chromatographic systems to indicate and identify antioxidants from Mallotus species",
    C. Tistaert, B. Dejaegher, G. Chataigné, M. Chau Van, J. Quetin-Leclercq, Y. Vander Heyden,
    Talanta 83 (2011) 1198-1208
    doi:10.1016/j.talanta.2010.11.027

  • [44] "Influence of putrescine, cadaverine, spermidine or spermine on the formation of N-nitrosamine in heated cured pork meat",
    G. Drabik-Markiewicz, B. Dejaegher, E. De Mey, T. Kowalska, H. Paelinck, Y. Vander Heyden,
    Food Chemistry 126 (2011) 1539-1545
    doi:10.1016/j.foodchem.2010.11.149

  • [45] "Rational use of stacking principles for signal enhancement in capillary electrophoretic separations of poliovirus samples",
    I. Oita, H. Halewyck, S. Pieters, B. Dejaegher, B. Thys, B. Rombaut, Y. Vander Heyden,
    Journal of Pharmaceutical and Biomedical Analysis 55 (2011) 135-145
    doi:10.1016/j.jpba.2010.12.032

  • [46] "Chromatographic separation techniques and data handling methods for herbal fingerprints: A review",
    C. Tistaert, B. Dejaegher, Y. Vander Heyden,
    Analytica Chimica Acta 690 (2011) 148-161
    doi:10.1016/j.aca.2011.02.023

  • [47] "Experimental designs and their recent advances in set-up, data interpretation, and analytical applications",
    B. Dejaegher, Y. Vander Heyden,
    Journal of Pharmaceutical and Biomedical Analysis 56 (2011) 141-158
    doi:10.1016/j.jpba.2011.04.023

  • [48] "Classification models for neocryptolepine derivatives as inhibitors of the beta-haematin formation",
    B. Dejaegher, L. Dhooghe, M. Goodarzi, S. Apers, L. Pieters, Y. Vander Heyden,
    Analytica Chimica Acta 705 (2011) 98-110 (Special Issue CAC-2010)
    doi:10.1016/j.aca.2011.04.019

  • [49] "Quality control of Citri reticulatae pericarpium: exploratory analysis and discrimination",
    C. Tistaert, L. Thierry, A. Szandrach, B. Dejaegher, G. Fan, M. Frédérich, Y. Vander Heyden,
    Analytica Chimica Acta 705 (2011) 111-122 (Special Issue CAC-2010)
    doi:10.1016/j.aca.2011.04.024

  • [50] "Chemical constituents of Mallotus macrostachyus growing in Vietnam and cytotoxic activity of some cycloartane derivatives",
    N. Nguyen Hoai, K. Phan Van, B. Ninh Khac, T. Nguyen Phuong, N. Nguyen Xuan, C. Nguyen Xuan, C. Tistaert, B. Dejaegher, Y. Vander Heyden, J. Quetin-Leclercq, T. Do Thi, M. Chau Van,
    Phytochemistry Letters 4 (2011) 348-352
    doi:10.1016/j.phytol.2011.07.007

  • [51] "Identification by LC-ESI-MS of Flavonoids Responsible for the Antioxidant Properties of Mallotus Species from Vietnam",
    V.N.T. Hong, C. Rivière, Q.T. Hong, G. Chataigné, N.N. Hoai, B. Dejaegher, C. Tistaert, T.N.T. Kim, K.P. Van, Y. Vander Heyden, M.C. Van, J. Quetin-Leclercq,
    Natural Product Communications 6 (2011) 813-818

  • [52]"Development and validation of a normal-phase HPTLC-densitometric method for the quantitative analysis of fluconazole in tablets",
    D. H. Shewiyo, E. Kaale, P. G. Risha, H. B. Sillo, B. Dejaegher, J. Smeyers-Verbeke, Y. Vander Heyden,
    Journal of Planar Chromatography - Modern TLC 24 (2011) 529-533

  • [53] "Potential antioxidant compounds in Mallotus species fingerprints. Part II: Fingerprint alignment, data analysis and peak identification",
    C. Tistaert, B. Dejaegher, G. Chataigné, C. Rivière, N. Nguyen Hoai, M. Chau Van, J. Quetin-Leclercq, Y. Vander Heyden,
    Analytica Chimica Acta 721 (2012) 35-43
    doi:10.1016/j.aca.2012.01.058

  • [54] "Feature selection methods in QSAR studies",
    M. Goodarzi, B. Dejaegher, Y. Vander Heyden,
    The Journal of AOAC international 95(3) (2012) 636-651
    doi: http://dx.doi.org/10.5740/jaoacint.SGE_Goodarzi

  • [55] "N-methyl-5-carboxamide-2-pyridone from Mallotus barbatus: a chemosystematic marker in the sub-tribe Rottlerinae of the Euphorbiaceae",
    C. Rivière, V. Nguyen Thi Hong, N. Nguyen Hoai, B. Dejaegher, C. Tistaert, K. Phan Van, Y. Vander Heyden, M. Chau Van, J. Quetin-Leclercq,
    Biochemical Systematics and Ecology 44 (2012) 212-215
    doi:10.1016/j.bse.2012.05.004

  • [56] "Multivariate data analysis to evaluate the fingerprint peaks responsible for the cytotoxic activity of Mallotus species",
    C. Tistaert, G. Chataigné, B. Dejaegher, C. Rivière, N. Nguyen Hoai, M. Chau Van, J. Quetin-Leclercq, Y. Vander Heyden,
    Journal of Chromatography B 910 (2012) 103-113
    doi: http://dx.doi.org/10.1016/j.jchromb.2012.10.001

  • [57] "Potentially antioxidant compounds indicated from Mallotus and Phyllanthus species fingerprints",
    S. Thiangthum, B. Dejaegher, M. Goodarzi, C. Tistaert, A.Y. Gordien, N. Nguyen Hoai, M. Chau Van, J. Quetin-Leclercq, L. Suntornsuk, Y. Vander Heyden,
    Journal of Chromatography B 910 (2012) 114-121
    doi: http://dx.doi.org/10.1016/j.jchromb.2012.06.025

  • [58] "HPTLC methods to assay active ingredients in pharmaceutical formulations: A review of the method development and validation steps",
    D.H. Shewiyo, E. Kaale, P.G. Risha, B. Dejaegher, J. Smeyers-Verbeke, Y. Vander Heyden,
    Journal of Pharmaceutical and Biomedical Analysis 66 (2012) 11-23
    doi:10.1016/j.jpba.2012.03.034

  • [59] "Optimization of a reversed-phase-high-performance thin-layer chromatography method for the separation of isoniazid, ethambutol, rifampicin and pyrazinamide in fixed-dose combination antituberculosis tablets,"
    D.H. Shewiyo, E. Kaale, P.G. Risha, B. Dejaegher, J. Smeyers-Verbeke, Y. Vander Heyden,
    Journal of Chromatography A 1260 (2012) 232-238
    doi: http://dx.doi.org/10.1016/j.chroma.2012.08.044

  • [60] "Accuracy profiles assessing the validity for routine use of high-performance thin-layer chromatographic assays for drug formulations",
    D. H. Shewiyo, E. Kaale, P. G. Risha, B. Dejaegher, J. De Beer, J. Smeyers-Verbeke, Y. Vander Heyden,
    Journal of Chromatography A 1293 (2013) 159-169
    doi: 10.1016/j.chroma.2013.03.074

Terug naar boven

Oral Presentations

    * On invitation

  • (1) "The variance of screening- and supersaturated- design results as a measure for the robustness of a method",
    B. Dejaegher, J. Smeyers-Verbeke, D.L. Massart, Y. Vander Heyden,
    12th Forum of Pharmaceutical Sciences - May 6th & 7th 2004 - Blankenberge - Belgium

  • (2) "La variance des résultats des plans de criblage et des plans super saturés comme mesure de la robustesse d'une méthode",
    B. Dejaegher, J. Smeyers-Verbeke, Y. Vander Heyden,
    30 ans de Méthodologie de la Recherche Expérimentale - June 2th & 3th 2005 - Aix en Provence - France

  • (3) "Supersaturated designs in robustness testing",
    B. Dejaegher,
    ChemoAC meeting - June 16th & 17th 2005 - VUB - Brussels - Belgium

  • (4) "La méthode 'Fixing Effects and Adding Rows' (FEAR) pour estimer les effets des facteurs dans les plans super saturés",
    B. Dejaegher, X. Capron, J. Smeyers-Verbeke, Y. Vander Heyden,
    Chimiométrie 2005 - November 30th & December 1st 2005 - Villeneuve d'Ascq - France

  • (5) "Test de robustesse: set-up expérimental et analyse des résultats",
    B. Dejaegher, Y. Vander Heyden,
    Forum LABO & Forum BIOTECH 2006 - March 28th-30th 2006 - Paris - France

  • (6) "FEAR method to estimate factor effects in supersaturated designs constructed from Plackett-Burman designs",
    B. Dejaegher, X. Capron, Y. Vander Heyden,
    10th International Conference on Chemometrics in Analytical Chemistry (CAC-2006) - Chemometrics in the Tropics: Nature, Medicine and Industry - September 10th-15th 2006 - Águas de Lindóia - Brazil

  • (7) "FEAR method to estimate factor effects in two-level supersaturated designs",
    B. Dejaegher, X. Capron, Y. Vander Heyden,
    10th Scandinavian Symposium on Chemometrics (SSC10) - June 11th-15th 2007 - Lappeenranta - Finland

  • (8) "Robustness testing of HPLC methods",
    B. Dejaegher, Y. Vander Heyden,
    31st International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2007) - June 17th-21st 2007 - Ghent - Belgium

  • (9) "FEAR method to estimate factor effects in two-level supersaturated designs",
    B. Dejaegher, X. Capron, Y. Vander Heyden,
    Conferentia Chemometrica 2007 - September 2th-5th 2007 - Budapest - Hungary

  • (10) "Capillary electrophoresis of poliovirus particles",
    I. Oita, H. Halewyck, B. Dejaegher, B. Rombaut, Y. Vander Heyden,
    13th Forum of Pharmaceutical Sciences - October 11th & 12th 2007 - Spa - Belgium

  • (11) "Identification of peaks from HPLC fingerprints responsible for the antioxidant activity of Mallotus species",
    B. Dejaegher, C. Tistaert, N. Nguyen Hoai, M. Chau Van, V. Nguyen Thi Hong, C. Rivière, J. Quetin-Leclercq, Y. Vander Heyden,
    11th conference on Chemometrics in Analytical Chemistry (CAC-2008) - June 30th-July 4th 2008 - Montpellier - France

  • * (12) "Supersaturated designs in robustness testing: FEAR method to estimate factor effects in two-level supersaturated designs",
    B. Dejaegher, J. Smeyers-Verbeke, Y. Vander Heyden,
    Business Economics Seminar - December 11th 2008 - Antwerp - Belgium

  • (13) "Pressurized capillary electrochromatography as an alternative technique to high-performance liquid chromatography for the indication of active compounds in Mallotus species",
    S. Pieters, K. Bodzioch, C. Tistaert, G. Alaerts, B. Dejaegher, D. Mangelings, Y. Vander Heyden,
    14th Forum of Pharmaceutical Sciences - May 14th-15th 2009 - Blankenberge - Belgium

  • (14) "Signal increase for a capillary electrophoresis separation of poliovirus particles",
    I. Oita, H. Halewyck, B. Dejaegher, B. Thys, B. Rombaut, Y. Vander Heyden,
    14th Forum of Pharmaceutical Sciences - May 14th-15th 2009 - Blankenberge - Belgium

  • (15) "Indication and identification of potential antioxidant compounds in Mallotus species fingerprints",
    C. Tistaert, B. Dejaegher, N. Nguyen Hoai, M. Chau Van, V. Nguyen Thi Hong, G. Chataigné, C. Rivière, J. Quetin-Leclercq, Y. Vander Heyden,
    14th Forum of Pharmaceutical Sciences - May 14th-15th 2009 - Blankenberge - Belgium

  • (16) "Challenges in capillary electrophoretic analysis of viral particles",
    I. Oita, H. Halewyck, B. Dejaegher, B. Thys, B. Rombaut, J. Smeyers-Verbeke, Y. Vander Heyden,
    Day of Pharmaceutical Research ("Dag van het Farmaceutisch Onderzoek") - June 2nd 2009 - Lamot Congres- en erfgoedcentrum - Mechelen - Belgium

  • (17) "Indication and identification of potential antioxidant compounds in Mallotus species fingerprints",
    C. Tistaert, B. Dejaegher, N. Nguyen Hoai, M. Chau Van, V. Nguyen Thi Hong, G. Chataigné, C. Rivière, J. Quetin-Leclercq, J. Smeyers-Verbeke, Y. Vander Heyden,
    Day of Pharmaceutical Research ("Dag van het Farmaceutisch Onderzoek") - June 2nd 2009 - Lamot Congres- en erfgoedcentrum - Mechelen - Belgium

  • (18) "Indication and identification of potential antioxidant compounds in Mallotus species fingerprints",
    C. Tistaert, B. Dejaegher, N. Nguyen Hoai, M. Chau Van, V. Nguyen Thi Hong, G. Chataigné, C. Rivière, J. Quetin-Leclercq, J. Smeyers-Verbeke, Y. Vander Heyden,
    11th Scandinavian Symposium on Chemometrics (SSC11) - June 8th-11th 2007 - Loen/Stryn - Norway

  • (19) "Factors influencing poliovirus focusing during a capillary electrophoresis separation",
    I. Oita, H. Halewyck, B. Dejaegher, B. Thys, B. Rombaut, Y. Vander Heyden,
    5th Conference by Nordic Separation Society - August 26th-29th 2009 - Tallin - Estonia
    Awarded with the Best young scientist award.

  • (20) "Assessment of different methods for cleaning up a fluorescent labelled poliovirus sample and analysis with laser induced fluorescent capillary electrophoresis",
    H. Halewyck, I. Oita, B. Thys, B. Dejaegher, Y. Vander Heyden, B. Rombaut,
    International Symposium on Hyphenated Techniques for Sample Preparation (HTSP) - January 26th-27th 2010 - Bruges - Belgium

  • (21) "Data handling of chromatographic herbal fingerprints",
    B. Dejaegher, Y. Vander Heyden,
    11th International Symposium on Hyphenated Techniques in Chromatography and Hyphenated Chromatographic Analyzers (HTC-11) - January 27th-29th 2010 - Brugge - Belgium

  • (22) "Identification of antioxidative compounds in Mallotus species combining chemometrical treated fingerprints with HPLC-MS",
    C. Tistaert, B. Dejaegher, G. Chataigné, N. Nguyen Hoai, C. Rivière, M. Chau Van, J. Quetin-Leclercq, Y. Vander Heyden,
    Belgian Society for Mass Spectrometry (BSMS) Annual Meeting 2010 - April 16th 2010 - Woluwé - Belgium

  • * (23) "Improving Method Capability of a Drug Substance HPLC Assay",
    B. Dejaegher, M. Jimidar, M. De Smet, P. Cockaerts, J. Smeyers-Verbeke, Y. Vander Heyden,
    Joint Pharmaceutical Analysis Group (JPAG) Meeting: Chemometrics and Multivariate Statistics in Pharmaceutical Development - Royal Pharmaceutical Society of Great Britain - April 22th 2010 - London - United Kingdom

  • (24) "Development and optimisation of separation methods for viral compound",
    I. Oita, H. Halewyck, S. Pieters, B. Dejaegher, B. Thys, B. Rombaut, Y. Vander Heyden,
    PhD Research Day 2010 ("Dag van de Doctorandi 2010") - May 28th 2010 - VUB - Brussels - Belgium

  • (25) "Chromatographic fingerprints for herbal extracts: set-up and data analysis",
    G. Alaerts, M. Dumarey, J. van Erps, S. Pieters, M. Merino-Arévalo, N. Matthijs, B. Dejaegher, J. Smeyers-Verbeke, Y. Vander Heyden,
    ISCNP-ISDNP 2010, 7th International Symposium on Chromatography of Natural Products, combined with the 6th International Symposium of the International Society for the Development of Natural Products: The application of analytical methods for the development of natural products - June 14th-17th 2010 - Lublin - Poland

  • (26) "Improving MS identification of Bacillus Subtilis delta-prpE and 168 proteins with the use of QSRR-based peptides retention times prediction in RP-HPLC",
    K. Macur, T. Baczek, R. Kaliszan, C. Tistaert, B. Dejaegher, Y. Vander Heyden,
    Drug analysis 2010 - September 21st-24th 2010 - University of Antwerp - Belgium

  • (27) "Data handling of chromatographic herbal fingerprints",
    B. Dejaegher, C. Tistaert, M. Dumarey, G. Alaerts, Y. Vander Heyden,
    12th International Conference on Chemometrics in Analytical Chemistry (CAC-2010) - October 18th-21th 2010 - Antwerp - Belgium

  • * (28) "Chromatographic herbal fingerprints: Development, Validation, and Data Handling",
    B. Dejaegher, C. Tistaert, M. Dumarey, G. Alaerts, Y. Vander Heyden,
    Research on fingerprints of Chinese Materia Medica to develop standard and research protocols evaluating their identity, safety, and reproducibility - December 17th 2010 - Brussels - Belgium

  • * (29) "Basic unsupervised and supervised multivariate data analysis",
    B. Dejaegher, C. Tistaert, M. Goodarzi, M. Dumarey, G. Alaerts, Y. Vander Heyden,
    Workshop Metabolomics: Basics and Applications to Plant Sciences - April 11th-15th 2011 - Leiden - The Netherlands

  • (30) "Development and validation of a normal-phase HPTLC method for the simultaneous analysis of lamivudine, stavudine and nevirapine in fixed dose combination tablets",
    D.H. Shewiyo, E. Kaale, C. Ugullum, M.N. Sigonda, P.G. Risha, B. Dejaegher, J. Smeyers-Verbeke, Y. Vander Heyden,
    15th Forum of Pharmaceutical Sciences - May 12th-13th 2011 - Spa - Belgium

  • (31) "Data analysis of HPLC fingerprints from Mallotus and Phyllanthus samples",
    S. Thiangthum, B. Dejaegher, M. Goodarzi, C. Tistaert, Y. Vander Heyden,
    15th Forum of Pharmaceutical Sciences - May 12th-13th 2011 - Spa - Belgium

  • * (32) "Experimental designs for the optimization of separation techniques",
    B. Dejaegher, Y. Vander Heyden,
    Master Class Separation Techniques in Life Sciences - May 18th 2011 - Breda - The Netherlands

  • * (33) "Chromatographic herbal fingerprints: development, validation and data handling",
    B. Dejaegher, C. Tistaert, M. Goodarzi, G. Alaerts, Y. Vander Heyden,
    Kwaliteitsaspecten van Geneeskrachtige Planten - Nederlandse Vereniging voor GeneeskruidenOnderzoek (NVGO) - May 27th 2011 - Strombeek-Bever - Belgium

  • (34) "Experimental Design-Based Method Development and its Translation to Chromatographic Methods",
    Y. Vander Heyden, B. Dejaegher, M. Dumarey, R. Sneyers, W. Janssens, I. Somers,
    HPLC 2011 - 36th International Symposium on High-Performance Liquid Phase Separations and Related Techniques -June 19th-23rd 2011 - Budapest - Hungary

  • (35) "Experimental Design-Based Method Development and its Translation to Chromatographic Methods",
    Y. Vander Heyden, B. Dejaegher, M. Dumarey, R. Sneyers, W. Janssens, I. Somers,
    ITP 2011 - 18th International Symposium on Electro- and Liquid Phase-separation Techniques - August 28th-31st 2011, Tbilisi - Georgia

  • (36) "Herbal fingerprints: development and extraction of information",
    Y. Vander Heyden, G. Alaerts, M. Dumarey, C. Tistaert, B. Dejaegher,
    RDPA2011 - 14th International Meeting on Recent Developments in Pharmaceutical Analysis - September 21st-24th 2011 - Pavia - Italy

  • * (37) "Experimental designs for the optimization of analytical techniques",
    B. Dejaegher, Y. Vander Heyden,
    South East Region Analytical Division and Chemometrics Group of the Royal Society of Chemistry Symposium: Practical Chemometrics for the Analytical Scientist - October 25th 2011 - Esher - United Kingdom

  • (38) "Herbal Fingerprints: Extraction of Information",
    Y. Vander Heyden, C. Tistaert, G. Alaerts, B. Dejaegher,
    Twelfth International Symposium on Hyphenated Techniques in Chromatography and Hyphenated Chromatographic Analysers (HTC-12) - February 1st-3rd 2012 - Bruges - Belgium

  • (39) "Experimental designs for the optimization of analytical techniques",
    B. Dejaegher, Y. Vander Heyden,
    Twelfth International Symposium on Hyphenated Techniques in Chromatography and Hyphenated Chromatographic Analysers (HTC-12) - February 1st-3rd 2012 - Bruges - Belgium

  • * (40) "Basic unsupervised and supervised multivariate data analysis",
    B. Dejaegher, C. Tistaert, M. Goodarzi, M. Dumarey, G. Alaerts, Y. Vander Heyden,
    Workshop Metabolomics: Basics and Applications to Plant Sciences - April 23th-27th 2012 - Leiden - The Netherlands

  • (41) "Data handling of chromatographic herbal fingerprints",
    B. Dejaegher, M. Goodarzi, G. Alaerts, C. Tistaert, M. Dumarey, Y. Vander Heyden,
    13th International Conference on Chemometrics in Analytical Chemistry (CAC-2012) - June 25th-29th 2012 - Budapest - Hungary

  • (42) "Comparison of different approaches for the optimization of two parameters of Radial Basis Function - Support Vector Machines for Classification",
    B. Dejaegher, C. Ruckebusch, O. Devos, Y. Vander Heyden,
    Chimiométrie 2012 - December 5th-6th 2012 - Villeneuve d'Ascq - France

  • * (43) "Basic unsupervised and supervised multivariate data analysis",
    B. Dejaegher, G. Alaerts, C. Tistaert, J. Viaene, M. Dumarey, Y. Vander Heyden,
    Workshop Metabolomics: Basics and Applications to Plant Sciences - April 15th-19th 2013 - Leiden - The Netherlands

  • (44) "Herbal Fingerprints: Development and Data Analysis",
    Y. Vander Heyden, G. Alaerts, M. Goodarzi, C. Tistaert, J. Viaene, B. Dejaegher,
    AFERP & STOLON International Symposium - May 22nd-24th 2013 - Brussels - Belgium

  • (45) "Herbal Fingerprints: Extraction of Information, Focussing on Similarity Analysis",
    Y. Vander Heyden, G. Alaerts, M. Dumarey, M. Goodarzi, C. Tistaert, B. Dejaegher,
    HPLC 2013 - 39th International Symposium on High-Performance-Liquid-Phase Separations and Related Techniques - June 16th-20th 2013 - Amsterdam - The Netherlands

  • (46) "Alternative methods for multi-objective optimization of Radial Basis Function - Support Vector Machines for Classification",
    B. Dejaegher, C. Ruckebusch, O. Devos, Y. Vander Heyden,
    VIII Colloquium Chemiometricum Mediterraneum - June 30th-July 4th 2013 - Bevagna - Italy

Terug naar boven

Poster Presentations

  • (1) "Evaluation of the applicability of the variance of screening- and supersaturated- design results as a measure for the robustness of a method",
    B. Dejaegher,
    ChemoAC meeting - January 15th & 16th 2004 - VUB - Brussels - Belgium

  • (2) "Estimation of factor effects in supersaturated designs - Preliminary Results",
    B. Dejaegher, X. Capron, M. Daszykowski, Y. Vander Heyden,
    ChemoAC meeting - June 10th & 11th 2004 - VUB - Brussels - Belgium

  • (3) "The variance of screening- and supersaturated- design results as a measure for the robustness of a method",
    B. Dejaegher, J. Smeyers-Verbeke, D.L. Massart, Y. Vander Heyden,
    9th International Conference on Chemometrics in Analytical Chemistry (CAC-2004) - September 20th-23th 2004 - Instituto Superior Técnico - Lisbon - Portugal

  • (4) "Chemometric techniques to determine 4-aminophenol in blue paracetamol tablets - Preliminary Results",
    B. Dejaegher, X. Capron, M.S. Bloomfield,
    ChemoAC meeting - December 9th & 10th 2004 - VUB - Brussels - Belgium

  • (5) "Identifying significant effects in experimental designs for robustness testing: randomization tests versus the algorithm of Dong",
    B. Dejaegher, J. Smeyers-Verbeke, Y. Vander Heyden,
    30 ans de Méthodologie de la Recherche Expérimentale - June 2th & 3th 2005 - Aix en Provence - France

  • (6) "FIA determination of 4-aminophenol in blue paracetamol tablets",
    B. Dejaegher, X. Capron, M.S. Bloomfield,
    ChemoAC meeting - June 16th & 17th 2005 - VUB - Brussels - Belgium

  • (7) "Identifying significant effects in experimental designs for robustness testing: randomization tests versus the algorithm of Dong",
    B. Dejaegher, J. Smeyers-Verbeke, Y. Vander Heyden,
    ChemoAC meeting - June 16th & 17th 2005 - VUB - Brussels - Belgium

  • (8) "Fixing Effects and Adding Rows (FEAR) method to estimate factor effects in supersaturated designs constructed from Plackett-Burman designs",
    B. Dejaegher, X. Capron, Y. Vander Heyden,
    8th Chemometrics Symposium - April 28th 2006 - Belgian Chemometrics Society - VUB - Brussels - Belgium

  • (9) "FIA assay for L-N-monomethylarginine: method validation and comparison of Plackett-Burman and supersaturated designs in robustness testing",
    B. Dejaegher, M. Dumarey, X. Capron, M.S. Bloomfield, Y. Vander Heyden,
    8th Chemometrics Symposium - April 28th 2006 - Belgian Chemometrics Society - VUB - Brussels - Belgium

  • (10) "FEAR method to estimate factor effects in supersaturated designs constructed from Plackett-Burman designs",
    B. Dejaegher, X. Capron, Y. Vander Heyden,
    10th International Conference on Chemometrics in Analytical Chemistry (CAC-2006) - Chemometrics in the Tropics: Nature, Medicine and Industry - September 10th-15th 2006 - Águas de Lindóia - Brazil

  • (11) "Validation and comparison of Plackett-Burman and supersaturated designs in robustness testing of a FIA assay",
    B. Dejaegher, M. Dumarey, X. Capron, M.S. Bloomfield, Y. Vander Heyden,
    10th International Conference on Chemometrics in Analytical Chemistry (CAC-2006) - Chemometrics in the Tropics: Nature, Medicine and Industry - September 10th-15th 2006 - Águas de Lindóia - Brazil

  • (12) "La méthode 'Fixing Effects and Adding Rows' (FEAR) pour estimer les effets des facteurs dans les plans supersaturés",
    B. Dejaegher, X. Capron, Y. Vander Heyden,
    Chimiométrie 2006 - November 30th & December 1st 2006 - Paris - France

  • (13) "Comparaison des plans de Plackett et Burman et des plans supersaturés dans des tests de robustesse",
    B. Dejaegher, M. Dumarey, X. Capron, M.S. Bloomfield, Y. Vander Heyden,
    Chimiométrie 2006 - November 30th & December 1st 2006 - Paris - France

  • (14) "‘Fixing Effects and Adding Rows’ (FEAR) method to estimate factor effects in supersaturated designs constructed from Plackett-Burman designs",
    B. Dejaegher, X. Capron, Y. Vander Heyden,
    23rd Annual Symposium on Chemometrics: Chemometrics for Food, Food for Chemometrics - May 31st 2007 - Wageningen - The Netherlands

  • (15) "‘Fixing Effects and Adding Rows’ (FEAR) method to estimate factor effects in supersaturated designs constructed from Plackett-Burman designs",
    B. Dejaegher, X. Capron, Y. Vander Heyden,
    International Conference on Design of Industrial Experiments - January 14th & 15th 2008 - Antwerpen - Belgium

  • (16) "Determination of antioxidative compounds in Mallotus species fingerprints using linear multivariate calibration techniques",
    C. Tistaert, B. Dejaegher, N. Nguyen Hoai, C. Riviere, V. Nguyen Thi Hong, M. Chau Van, J. Quetin-leclercq, Y. Vander Heyden,
    9th Chemometrics Symposium of the Belgian Chemometrics Society - April 11th 2008 - Gembloux - Belgium

  • (17) "Capillary electrophoresis of poliovirus particles",
    H. Halewyck, I. Oita, B. Thys, B. Dejaegher, Y. Vander Heyden, B. Rombaut,
    Europic 2008: 15th Meeting of European Study Group on the Molecular Biology of Picornaviruses - May 26th-30th 2008 - Sitges - Barcelona - Spain

  • (18) "Determination of antioxidative compounds in Mallotus species fingerprints using linear multivariate calibration techniques",
    C. Tistaert, B. Dejaegher, N. Nguyen Hoai, C. Riviere, V. Nguyen Thi Hong, M. Chau Van, J. Quetin-leclercq, Y. Vander Heyden,
    19th International Symposium on Pharmaceutical and Biomedical Analysis - June 8th-12th 2008 - Gdansk - Poland

  • (19) "Influence of sample matrix composition on the separation efficiency of poliovirus particles in capillary electrophoresis",
    I. Oita, H. Halewyck, B. Dejaegher, B. Thys, B. Rombaut, Y. Vander Heyden,
    19th International Symposium on Pharmaceutical and Biomedical Analysis - June 8th-12th 2008 - Gdansk - Poland

  • (20) "Separation of poliovirus particles using capillary electrophoresis",
    B. Rombaut, H. Halewyck, I. Oita, B. Thys, B. Dejaegher, Y. Vander Heyden,
    International Union of Microbiological Sciences: meeting of the three divisions - August 11th-15th 2008 - Istanbul - Turkey

  • (21) "Process Understanding and Process Efficiency Increase of Freeze Drying",
    T. De Beer, M. Wiggenhorn, R. Veillon, C. Debacq, P. Vercruysse, A. Burggraeve, B. Dejaegher, Y. Vander Heyden, W. Friess, C. Vervaet, J.P. Remon, W.R.G. Baeyens,
    Hands-on Implementation of Process Analytical Technology (PAT) systems in Production Processes - August 25th-26th 2008 - Gent - Belgium

  • (22) "Evaluation of sample matrix components affecting the separation efficiency of poliovirus particles in capillary electrophoresis",
    I. Oita, H. Halewyck, B. Dejaegher, S. Pieters, B. Thys, B. Rombaut, Y. Vander Heyden,
    16th international symposium on capillary electroseparation techniques (ITP2008) - August 31st-September 4th 2008 - Catania - Italy

  • (23) "On-line sample preconcentration of poliovirus particles in a capillary electrophoresis method",
    I. Oita, H. Halewyck, B. Dejaegher, S. Pieters, B. Thys, B. Rombaut, Y. Vander Heyden,
    16th international symposium on capillary electroseparation techniques (ITP2008) - August 31st-September 4th 2008 - Catania - Italy

  • (24) "Antioxidant properties of Mallotus species from Vietnamese mountainous areas",
    C. Rivière, V. Nguyen Thi Hong, Q. Tran Hong, G. Chataigné, N. Nguyen Hoai, T. Nguyen Thi Kim, B. Dejaegher, Y. Vander Heyden, M. Chau Van, J. Quetin-Leclercq,
    Plants from High Altitude - Phytochemistry and Bioactivity - April 26th-29th 2009 - University Centre Obergurgl/Tyrol - Austria

  • (25) "Screening for antioxidant compounds in pressurized capillary electrochromatography fingerprints from Mallotus species using partial least squares algorithms",
    S. Pieters, K. Bodzioch, C. Tistaert, G. Alaerts, B. Dejaegher, D. Mangelings, Y. Vander Heyden,
    25th Annual Symposium on Chemometrics: Dynamic chemometrics - May 28th 2009 - Delft - The Netherlands

  • (26) "Indication and identification of potential antioxidant compounds in Mallotus species fingerprints",
    C. Tistaert, B. Dejaegher, N. Nguyen Hoai, M. Chau Van, V. Nguyen Thi Hong, G. Chataigné, C. Rivière, J. Quetin-Leclercq, J. Smeyers-Verbeke, Y. Vander Heyden,
    25th Annual Symposium on Chemometrics: Dynamic chemometrics - May 28th 2009 - Delft - The Netherlands

  • (27) "Dissimilar chromatographic systems to identify peaks responsible for the antioxidant activity of Mallotus species",
    C. Tistaert, B. Dejaegher, P. Doan Lan, C. Rivière, M. Chau Van, J. Quetin-Leclercq, Y. Vander Heyden,
    11th Scandinavian Symposium on Chemometrics (SSC11) - June 8th-11th 2009 - Loen/Stryn - Norway
    Awarded as runner-up for the Wiley Award for the best poster.

  • (28) "Signal increase using experimental design for a capillary electrophoresis separation of poliovirus particles",
    I. Oita, H. Halewyck, C. Tistaert, B. Dejaegher, S. Pieters, B. Thys, B. Rombaut, Y. Vander Heyden,
    11th Scandinavian Symposium on Chemometrics (SSC11) - June 8th-11th 2009 - Loen - Norway

  • (29) "Screening for antioxidant compounds in Mallotus species using partial least squares regression models built on pressurized capillary electrochromatography fingerprints",
    S. Pieters, K. Bodzioch, C. Tistaert, G. Alaerts, B. Dejaegher, D. Mangelings, Y. Vander Heyden,
    PhD course on Process Analytical Technology, Technical University of Denmark (DTU) - June 21-26th 2009 - Lyngby - Denmark

  • (30) "Pressurized capillary electrochromatography, a useful technique to screen for antioxidant compounds in Mallotus fingerprints?",
    S. Pieters, K. Bodzioch, C. Tistaert, G. Alaerts, B. Dejaegher, D. Mangelings, Y. Vander Heyden,
    Recent Developments in Pharmaceutical Analysis (RDPA) 2009, 13th international meeting - September 9-12th 2009 - Milan - Italy

  • (31) "Dissimilar chromatographic fingerprints to indicate compounds with antioxidant activity",
    C. Tistaert, B. Dejaegher, G. Chataigné, P. Doan Lan, C. Rivière, M. Chau Van, J. Quetin-Leclercq, Y. Vander Heyden,
    Chimiométrie 2009 - November 30th & December 1st 2009 - Paris - France

  • (32) "Clean-up of poliovirus samples for capilary electrophoresis analysis using off-line spin-column size-exclusion chromatography",
    I. Oita, H. Halewyck, B. Dejaegher, B. Rombaut, Y. Vander Heyden,
    International Symposium on Hyphenated Techniques for Sample Preparation (HTSP) - January 26th-27th 2010 - Brugge - Belgium

  • (33) "Investigations on the stability of poliovirus in the presence of chemical interfering agents",
    I. Oita, H. Halewyck, B. Dejaegher, B. Thys, B. Rombaut, Y. Vander Heyden,
    24th International Symposium on Microscale Bioseparations (MSB2010) - March 21th-25th 2010 - Prague - Czech Republic

  • (34) "Fluorescence labeling of Poliovirus and analysis with laser induced capillary electrophoresis",
    H. Halewyck, I. Oita, L. Schotte, B. Thys, B. Dejaegher, Y. Vander Heyden, B. Rombaut,
    Microscale Bioseparations - March 21th-25th 2010 - Prague - Czech Republic

  • (35) "Screening for critical process parameters in a pharmaceutical freeze-drying process using a Plackett-Burman design and PAT tools",
    Sigrid Pieters, Thomas De Beer, Dorien Boulpaep, Bieke Dejaegher and Yvan Vander Heyden,
    26th Annual Symposium on Chemometrics: Knowledge integration & visualization - May 20th 2010 - Utrecht - The Netherlands

  • (36) "Identification of antioxidative compounds in Mallotus species combining chemometrical treated fingerprints with HPLC-MS ",
    C. Tistaert, B. Dejaegher, G. Chataigné, N. Nguyen Hoai, C. Rivière, V. Nguyen Thi Hong, M. Chau Van, J. Quetin-Leclercq, Y. Vander Heyden,
    26th Annual Symposium on Chemometrics: Knowledge integration & visualization - May 20th 2010 - Utrecht - The Netherlands

  • (37) "Development of a quantitative structure-activity relationship: estrogen receptor B ligands",
    T. Geerts, B. Dejaegher, Y. Vander Heyden,
    26th Annual Symposium on Chemometrics: Knowledge integration & visualization - May 20th 2010 - Utrecht - The Netherlands

  • (38) "Screening for critical process parameters in a pharmaceutical freeze-drying process using a Plackett-Burman design and PAT tools",
    Sigrid Pieters, Thomas De Beer, Dorien Boulpaep, Bieke Dejaegher and Yvan Vander Heyden,
    PhD Research Day 2010 ("Dag van de Doctorandi 2010") - May 28th 2010 - VUB - Brussels - Belgium

  • (39) "Identification of antioxidative compounds in Mallotus species combining chemometrical treated fingerprints with HPLC-MS ",
    C. Tistaert, B. Dejaegher, G. Chataigné, N. Nguyen Hoai, C. Rivière, V. Nguyen Thi Hong, M. Chau Van, J. Quetin-Leclercq, Y. Vander Heyden,
    PhD Research Day 2010 ("Dag van de Doctorandi 2010") - May 28th 2010 - VUB - Brussels - Belgium

  • (40) "Development of a quantitative structure-activity relationship: estrogen receptor B ligands",
    T. Geerts, B. Dejaegher, Y. Vander Heyden,
    PhD Research Day 2010 ("Dag van de Doctorandi 2010") - May 28th 2010 - VUB - Brussels - Belgium

  • (41) "Fluorescence labelling of poliovirus and analysis with laser induced fluorescence capillary electrophoresis",
    H. Halewyck, I. Oita, L. Schotte, B. Thys, B. Dejaegher, Y. Vander Heyden, B. Rombaut,
    PhD Research Day 2010 ("Dag van de Doctorandi 2010") - May 28th 2010 - VUB - Brussels - Belgium

  • (42) "Fluorescent poliovirus analysis with laser induced fluorescent capillary electrophoresis: Labeling efficiency versus viral properties",
    H. Halewyck, I. Oita, L. Schotte, B. Thys, B. Dejaegher, Y. Vander Heyden, B. Rombaut,
    EUROPIC 2010: 16th Meeting of the European Study Group on the Molecular Biology of Picornaviruses - September 11-16th 2010 - St. Andrews - Scotland

  • (43) "Comparing different descriptor selection strategies in QSRR to predict the chromatographic retention of diverse drugs",
    M. Goodarzi, B. Dejaegher, Y. Vander Heyden,
    12th International Conference on Chemometrics in Analytical Chemistry (CAC-2010) - October 18th-21th 2010 - Antwerp - Belgium

  • (44) "Exploring 2D and 3D QSAR models of thiocarbamates, a new class of potent non-nucleosides HIV-1 reverse transcriptase inhibitors",
    M. Goodarzi, B. Dejaegher, Y. Vander Heyden,
    12th International Conference on Chemometrics in Analytical Chemistry (CAC-2010) - October 18th-21th 2010 - Antwerp - Belgium

  • (45) "Development of a quantitative structure-activity relationship: estrogen receptor B ligands",
    T. Geerts, B. Dejaegher, Y. Vander Heyden,
    12th International Conference on Chemometrics in Analytical Chemistry (CAC-2010) - October 18th-21th 2010 - Antwerp - Belgium

  • (46) "Quality control of Citri reticulatae pericarpium based on chemometrically treated HPLC fingerprints",
    C. Tistaert, A. Szandrach, L. Thierry, B. Dejaegher, Y. Vander Heyden,
    12th International Conference on Chemometrics in Analytical Chemistry (CAC-2010) - October 18th-21th 2010 - Antwerp - Belgium

  • (47) "Classification models for neocryptolepine derivatives as inhibitors of the B-haematin formation",
    B. Dejaegher, L. Dhooghe, M. Goodarzi, S. Apers, L. Pieters, Y. Vander Heyden,
    12th International Conference on Chemometrics in Analytical Chemistry (CAC-2010) - October 18th-21th 2010 - Antwerp - Belgium

  • (48) "Quality control of Citri reticulatae: exploratory analysis and discrimination",
    C. Tistaert, A. Szandrach, L. Thierry, B. Dejaegher, Y. Vander Heyden,
    12th Research Unlimited - April 5th 2011 - Brussels - Belgium

  • (49) "Uniform designs in method optimization",
    B. Dejaegher and Y. Vander Heyden,
    12th Scandinavian Symposium on Chemometrics (SSC12) - June 7th-10th 2011 - Billund - Denmark

  • (50) "Classification models for neocryptolepine derivatives as inhibitors of the B-haematin formation",
    B. Dejaegher, L. Dhooghe, M. Goodarzi, S. Apers, L. Pieters, Y. Vander Heyden,
    12th Scandinavian Symposium on Chemometrics (SSC12) - June 7th-10th 2011 - Billund - Denmark

  • (51) "Data handling of chromatographic herbal fingerprints",
    B. Dejaegher, C. Tistaert, M. Dumarey, G. Alaerts, Y. Vander Heyden,
    12th Scandinavian Symposium on Chemometrics (SSC12) - June 7th-10th 2011 - Billund - Denmark

  • (52) "Fuzzy Rough Set as feature selection for QSAR modeling of 2,4,5-trisubstituted imidazoles, nontoxic modulators of P-glycoprotein mediated multidrug resistance",
    M Goodarzi, S. Funar-Timofei, B. Dejaegher, R. Jensen, Y. Vander Heyden,
    12th Scandinavian Symposium on Chemometrics (SSC12) - June 7th-10th 2011 - Billund - Denmark

  • (53) "Comparing different descriptor selection strategies in QSRR model building to predict the chromatographic retention of diverse drugs",
    M Goodarzi, B. Dejaegher, Y. Vander Heyden,
    12th Scandinavian Symposium on Chemometrics (SSC12) - June 7th-10th 2011 - Billund - Denmark

  • (54) "Quality control of Citri reticulatae: exploratory analysis and discrimination",
    C. Tistaert, A. Szandrach, L. Thierry, B. Dejaegher, Y. Vander Heyden,
    12th Scandinavian Symposium on Chemometrics (SSC12) - June 7th-10th 2011 - Billund - Denmark

  • (55) "Quality control of Citri reticulatae: exploratory analysis and discrimination",
    C. Tistaert, A. Szandrach, L. Thierry, B. Dejaegher, Y. Vander Heyden,
    34th Symposium on Chromatographic methods of investigating the organic compounds - June 8th-10th 2011 - Szczyrk - Poland

  • (56) "Classification of HPLC fingerprints for a set of Mallotus and Phyllanthus samples",
    M. Goodarzi, B. Dejaegher, C. Tistaert, A. Hoang Le Tuan, N. Nguyen Hoai, M. Chau Van, J. Quetin-Leclercq, Y. Vander Heyden,
    Fifth International Chemometrics Research Meeting (ICRM 2011) - September 25th-29th 2011 - Berg en Dal - The Netherlands

  • (57) "Tools for semi-supervised classification",
    B. Dejaegher, O. Devos, C. Ruckebusch, Y. Vander Heyden,
    13th International Conference on Chemometrics in Analytical Chemistry (CAC-2012) - June 25th-29th 2012 - Budapest - Hungary

  • (58) "Classification models for neocryptolepine derivatives as inhibitors of the B-haematin formation",
    B. Dejaegher, L. Dhooghe, M. Goodarzi, S. Apers, L. Pieters, Y. Vander Heyden,
    13th International Conference on Chemometrics in Analytical Chemistry (CAC-2012) - June 25th-29th 2012 - Budapest - Hungary

  • (59) "Fuzzy Rough Set as feature selection for QSAR modeling of 2,4,5-trisubstituted imidazoles, nontoxic modulators of P-glycoprotein mediated multidrug resistance",
    M Goodarzi, S. Funar-Timofei, R. Jensen, S. Pieters, B. Dejaegher,Y. Vander Heyden,
    13th International Conference on Chemometrics in Analytical Chemistry (CAC-2012) - June 25th-29th 2012 - Budapest - Hungary

  • (60) "Identification, discrimination, and classification of herbal samples using their chromatographic fingerprints",
    J. Viaene, G. Alaerts, B. Dejaegher, Y. Vander Heyden,
    Chimiométrie 2012 - December 5th-6th 2012 - Villeneuve d'Ascq - France

  • (61) "Identification, discrimination and classification of herbal samples using their chromatographic fingerprints",
    J. Viaene, G. Alaerts, B. Dejaegher, Y. Vander Heyden,
    Symposium 'Nieuwe ontwikkelingen in de scheidingsmethoden' - Werkgroep Scheidingsmethoden (WGS) of the Section Analytical Chemistry (SAC) of the Royal Netherlands Society of Chemistry (KNCV) - April 19th 2013 - Leiden - The Netherlands

  • (62) "Transfer of a chiral CE method using precision- and robustness-testing data",
    B. De Cock, B. De Meuter, B. Dejaegher, D. Mangelings, Y. Vander Heyden,
    Symposium 'Nieuwe ontwikkelingen in de scheidingsmethoden' - Werkgroep Scheidingsmethoden (WGS) of the Section Analytical Chemistry (SAC) of the Royal Netherlands Society of Chemistry (KNCV) - April 19th 2013 - Leiden - The Netherlands

  • (63) "Transfer of a chiral CE method using precision- and robustness-testing data",
    B. De Cock, B. De Meuter, B. Dejaegher, D. Mangelings, Y. Vander Heyden,
    Capillary Electrophoresis Users Meeting - Section Analytical Chemistry (SAC) of the Royal Netherlands Society of Chemistry (KNCV) and of the Royal Flemisch Society of Chemistry (KVCV) - April 26th 2013 - Breda - The Netherlands

  • (64) "Department Analytical Chemistry and Pharmaceutical Technology (FABI)",
    D. Mangelings, B. Dejaegher, B. De Cock, K. De Klerck, S. Pieters, J. Viaene, D. Alblas, Y. Vander Heyden,
    PhD Research Day 2013 - May 31st 2013 - VUB - Brussels - Belgium

  • (65) "Identification, discrimination and classification of Curcuma samples using their chromatographic fingerprints",
    J. Viaene, G. Alaerts, B. Dejaegher, Y. Vander Heyden,
    PhD Research Day 2013 - May 31st 2013 - VUB - Brussels - Belgium

  • (66) "Interinstrumental transfer of a chiral CE method using precision-studies and robustness-testing data",
    B. De Cock, B. De Meuter, B. Dejaegher, D. Mangelings, Y. Vander Heyden,
    PhD Research Day 2013 - May 31st 2013 - VUB - Brussels - Belgium

  • (67) "Precision optimisation of chiral capillary electrophoretic methods: constant current mode",
    B. De Cock, B. Dejaegher, D. Mangelings, Y. Vander Heyden,
    HPLC 2013 - 39th International Symposium on High-Performance-Liquid-Phase Separations and Related Techniques - June 16th-20th 2013 - Amsterdam - The netherlands

  • (68) "Identification, discrimination and classification of Curcuma samples using their chromatographic fingerprints",
    J. Viaene, G. Alaerts, B. Dejaegher, Y. Vander Heyden,
    HPLC 2013 - 39th International Symposium on High-Performance-Liquid-Phase Separations and Related Techniques - June 16th-20th 2013 - Amsterdam - The netherlands

Terug naar boven

Memberships

Terug naar boven

Coordinates

Bieke Dejaegher
Vrije Universiteit Brussel
Faculty of Medicines and Pharmacy (Faculteit Geneeskunde en Farmacie)
Center for Pharmaceutical Research (CePhaR) (Farmaceutisch Instituut)
Department of Analytical Chemistry and Pharmaceutical Technology (FABI) (Vakgroep Analytische Scheikunde en Farmaceutische Technologie)
Laarbeeklaan 103
B-1090 Brussels Belgium
Tel: (+32) 2 477 43 29
Fax: (+32) 2 477 47 35
Email: Bieke.Dejaegher@vub.ac.be

©1997-2005 • FABI • Vrije Universiteit Brussel • Faculteit Geneeskunde & Farmacie
Laarbeeklaan 103 • 1090 Jette • Tel.: 02/477.47.37 • Fax.: 02/477.47.35 • fabi@vub.ac.be